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Clinical Trials

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Cancer research helps find new ways to prevent, diagnose, treat, and manage all stages of cancer. Clinical trials are an important part of this process. When you take part in a clinical trial, you help researchers learn more about cancer and help make cancer care better for future patients.

To learn what your clinical trial options are, ask your oncologist whether there are any clinical trials that might be a good fit for you.

Learn More:

Visit the It Starts with Me website for general information about clinical trials.






Clinical Trials available at THP

Disease Site:

Disease Site: BREAST
Study:
pionERA (CO44657) Roche PI: Dr. Mala Bahl

Protocol: Phase III, Randomized, Open-Label Study Evaluating Efficacy and Safety of Giredestrant Compared with Fulvestrant, Both Combined with a CDK4/6 Inhibitor, in Patients with Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer with Resistance to Prior Adjuvant Endocrine Therapy

clinicaltrials.gov Link: NCT06065748

Disease Site: GI - HEPATOCELLULAR
Study:
HE.2 (SLIDE-HCC) CCTG PI: Dr. Mala Bahl

A Phase II Study of Stride (Durvalumab + Tremelimumab) with Lenvatinib Versus Stride Alone in Patients with Unrestectable Hepatocellular Carcinoma

clinicaltrials.gov Link: NCT06880523

Disease Site: GU - PROSTATE
Study:
PCS XI (CHU) RADIATION PI: Dr. Sarah Rauth

Pelvic nodes Ultra-Hypo Fractionated versus conventionally fractionated IMRT with HDR brachytherapy boost in prostate cancer: A collaborative multi-institutional non-inferiority phase 3 trial.

clinicaltrials.gov Link: NCT05820633

Disease Site: GU - PROSTATE
Study:
PR.24 (ASCENDE-SBRT) CCTG PI: Dr. Jasper Yuen

Androgen Suppression Combined with Elective Nodal Irradiation and Dose Escalated Prostate Treatment: A Non-Inferiority, Phase III Randomized Controlled Trial of Stereotactic Body Radiation Therapy versus Brachytherapy Boost in Patients with Unfavourable Risk Localized Prostate Cancer

clinicaltrials.gov Link: NCT05820633

Disease Site: GU - PROSTATE
Study:
PR.26 (TRIPLE-SWITCH) CCTG PI: Dr. Mary Mahler

A Randomized Phase III Clinical Trial for the Addition of Docetaxel to Androgen Receptor Pathway Inhibitors in Patients with Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

clinicaltrials.gov Link: NCT06592924

Disease Site: GYNE - ADJUVANT ENDOMETRIAL
Study:
EN.10 (CCTG) SURG/RADIATION PI: Dr. Kate Pulman

A Phase II Study of Tailored Adjuvant Therapy in Pole-mutated And P53-wildtype/SNMP Early Stage Endometrial Cancer (RAINBO BLUE & TAPER)

SUBSTUDY A:
RAINBO POLEmut-BLUE: Refining Adjuvant treatment IN endometrial cancer Based On molecular features (RAINBO) TransPORTEC platform trials

SUBSTUDY B:
Tailored Adjuvant Therapy in p53-Wildtype/NSMP Early Stage Endometrial Cancer (TAPER)

clinicaltrials.gov Link: NCT05640999

Disease Site: LUNG - METASTATIC NSCLC
Study:
MK-2870-007 (Merck) PI: Dr. Daniel Yokom

A randomized, open-label, phase 3 study of MK-2870 in combination with pembrolizumab compared to pembrolizumab monotherapy in the first-line treatment of participants with metastatic non-small cell lung cancer with PD-L1 TPS greater than or equal to 50% (TroFuse-007)

clinicaltrials.gov Link: NCT06170788

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